A clinical trial listing update dated September 25, 2026 shows a study registered as NCT07585721 is currently recruiting participants. The trial is titled "Postoperative Pain and Substance P Levels After Bioceramic vs Calcium Hydroxide Intracanal Medicaments in Symptomatic Apical Periodontitis." The listed phase is not applicable, indicating the study is not a traditional drug-phase clinical trial. The study focuses on comparing two intracanal medicament types, bioceramic and calcium hydroxide, in patients with symptomatic apical periodontitis. According to the listing, researchers plan to measure postoperative pain outcomes alongside substance P levels as part of the study design.
Substance P remains classified as an unapproved research compound. No results have been posted for this trial as of the listed date, and the study status remains recruiting. This means the trial is actively enrolling participants rather than reporting findings. No efficacy or safety conclusions can be drawn from a recruiting status alone.
Readers interested in the broader context of this compound can consult the substance P overview page for additional background information.