Publication August 25, 2026

MOTS-c Featured in Systematic Review on Exercise-Activated Peptides

A systematic review titled "Mitochondrial-derived peptides (MDPs) activated by physical exercise as therapeutic targets for metabolic disorders" was published on August 25, 2026. The review appeared in the journal Physiology International. MOTS-c is discussed within this review as one of the mitochondrial-derived peptides examined in relation to physical exercise and metabolic disorders. The publication is indexed under PubMed ID 42640735. As a systematic review, the article compiles and evaluates existing research on this topic rather than presenting new experimental results. No specific findings, outcomes, or conclusions from the review have been detailed here beyond its stated title and scope. MOTS-c remains classified as an unapproved compound intended for research purposes only. This publication contributes to the broader scientific literature examining mitochondrial-derived peptides and their potential relevance to metabolic health research. Readers interested in the specific content, methodology, and conclusions of this systematic review are encouraged to consult the full text through the journal or the linked source. For additional background on MOTS-c, readers can refer to the compound overview for further context.

See the full mots-c overview

Source: https://pubmed.ncbi.nlm.nih.gov/42640735/