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Research / Unapproved

MOTS-c Peptide: Research Status and Clinical Trial Data

Molecular formulaC101H152N28O22S2
Molecular weight2174.6 g/mol
Registered trials9
PubChem CID146675088

What MOTS-c Is

MOTS-c is a peptide compound identified by PubChem CID 146675088, with a molecular formula of C101H152N28O22S2. It has no FDA-approved drug label, and no brand name, indication, or mechanism has been officially established through that process. MOTS-c is currently classified as an unapproved research compound. Any information available about it comes from registered clinical trial activity rather than an approved prescribing label.

Clinical Trial Footprint

There are 9 registered clinical trials referencing MOTS-c. Among the sampled studies, one is recruiting participants to compare general anesthesia and combined spinal-epidural anesthesia with respect to ferroptosis, humanin, and MOTS-c levels during renal transplantation. Other listed studies, including a deafness-gene screening cohort and a vestibular implantation outcomes study, appear in the same trial registry search but do not center MOTS-c as the primary subject of investigation. No phase designation is reported for these studies.

FAQ

Is MOTS-c an FDA-approved drug?
No. MOTS-c has no FDA-approved label, brand name, or approved indication. It is currently studied only in a research context.
What is MOTS-c used for?
There is no approved use for MOTS-c. It appears in registered clinical trials, including studies examining its levels during anesthesia and organ transplantation procedures, but this does not establish an approved therapeutic use.
How many clinical trials involve MOTS-c?
Registry data shows 9 clinical trials referencing MOTS-c. These trials vary in focus, and not all use MOTS-c as the primary study subject.
What is the chemical identity of MOTS-c?
MOTS-c is a peptide with the molecular formula C101H152N28O22S2 and is catalogued under PubChem CID 146675088. This chemical identity is documented independently of any approval status.
Are there known side effects of MOTS-c?
No side effect reporting data is currently available for MOTS-c. Because it lacks an approved label, no official safety profile has been established.
This page is an editorial information resource. It does not sell, prescribe, or recommend any medication. Content is editorial information, not medical advice. Talk to your doctor before any treatment decision.

Sources: PubChem ClinicalTrials.gov

Updated 2026-09-19