New Meta-Analysis Compares Bivalirudin to Heparin/Protamine in Cardiac Surgery

A systematic review and meta-analysis examining bivalirudin versus heparin and protamine in adult patients undergoing cardiac surgery was published on October 1, 2026. The publication appeared in the journal Annals of Cardiac Anaesthesia. The study is identified as a systematic review and meta-analysis, a research method that pools data from multiple existing studies. Bivalirudin is an approved anticoagulant compound. This publication adds to the body of literature evaluating anticoagulation strategies used during cardiac surgical procedures. No specific findings, outcomes, or conclusions from the analysis are detailed here. Readers interested in the full scope of the comparison and its reported results should consult the original publication directly through the listed source. For additional background on bivalirudin, including its approved regulatory status and general profile, readers can refer to the compound overview.