Research / Unapproved

Thymosin Alpha-1: Research Status and Clinical Trial Data

Molecular formulaC129H215N33O55
Molecular weight3108.3 g/mol
Registered trials66
PubChem CID16130571

Regulatory status

Thymosin alpha-1 does not have an approved drug label. It is classified as an unapproved research compound, and no indications, dosing, or safety information have been established through an approved regulatory review.

What thymosin alpha-1 is

Thymosin alpha-1 is a peptide with the molecular formula C129H215N33O55 and a molecular weight of approximately 3,108.3 daltons (PubChem CID 16130571). Because it lacks an approved label, there is no FDA-sanctioned description of its mechanism, indicated uses, or approved brand names.

Trial footprint

There are 66 registered clinical trials referencing thymosin alpha-1. Sampled studies illustrate the range of conditions under investigation rather than any established use. One phase 2 trial examining an abscopal effect in metastatic colorectal cancer was withdrawn. A phase 3 trial testing recombinant human interferon alpha nasal drops, studied alongside thymosin alpha-1 research contexts, to prevent 2019-nCOV infection in medical staff carries an unknown status. A separate trial evaluating long-term outcomes in sepsis patients after immunotherapy has not yet begun recruiting.

FAQ

Is thymosin alpha-1 FDA approved?
No. Thymosin alpha-1 does not have an approved drug label in the data reviewed here. It remains classified as an unapproved research compound.
What is thymosin alpha-1 studied for?
Registered trials have explored contexts such as cancer immunotherapy, sepsis outcomes, and viral infection prevention. These are research investigations only and do not indicate a proven or approved use.
How many clinical trials involve thymosin alpha-1?
There are 66 registered clinical trials referencing thymosin alpha-1. Trial statuses vary, including withdrawn, not yet recruiting, and unknown status.
What is the molecular structure of thymosin alpha-1?
Thymosin alpha-1 has the molecular formula C129H215N33O55 and a molecular weight of about 3,108.3 daltons. It is catalogued in PubChem under CID 16130571.
Are there known side effects of thymosin alpha-1?
No adverse event report data was available in the dataset reviewed for this monograph. This does not confirm the absence of side effects, only that no report data was provided here.
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Sources: PubChem ClinicalTrials.gov

Updated 2026-09-19