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Research / Unapproved

Tesofensine: Research Status, Uses, and Trial Data

Molecular formulaC17H23Cl2NO
Molecular weight328.3 g/mol
Registered trials13
PubChem CID11370864

What tesofensine is

Tesofensine is a chemical compound identified by PubChem CID 11370864, with the molecular formula C17H23Cl2NO. It has no FDA-approved label and no approved brand name in the United States. Any information about it reflects research data only, not established medical guidance.

Regulatory and development status

Tesofensine is unapproved and remains in the research and clinical trial stage. It has not been cleared by the FDA for any indication, and no dosing or use recommendations can be drawn from available data.

Trial footprint

Thirteen trials involving tesofensine are registered. Among the sampled studies, one Phase 1 trial examined its effect alongside metoprolol on 24-hour mean heart rate, and another combined Phase 1/Phase 2 trial looked at its effect on energy balance in humans. A separate Phase 2 study evaluated tesofensine in early Parkinson's disease patients as part of a placebo-controlled dose-response design. These trials are completed, but completion of a trial does not by itself establish safety or effectiveness for any use.

FAQ

Is tesofensine FDA approved?
No. Tesofensine has no FDA-approved label or brand name. It remains classified as an investigational compound studied only in clinical research settings.
What has tesofensine been studied for?
Registered trials have examined tesofensine's effects on heart rate in combination with metoprolol, its role in energy balance, and its use in early Parkinson's disease. These are research studies, not established treatment uses.
How many clinical trials have tested tesofensine?
There are 13 registered trials involving tesofensine. The sampled studies span Phase 1 through Phase 2 and are listed as completed.
Does completed trial status mean tesofensine works?
No. A completed trial status only means the study finished; it does not confirm that tesofensine is safe or effective for any condition. No approved indication currently exists.
What is the chemical identity of tesofensine?
Tesofensine has the molecular formula C17H23Cl2NO and is catalogued under PubChem CID 11370864. This identifier can be used to look up its chemical structure and properties.
This page is an editorial information resource. It does not sell, prescribe, or recommend any medication. Content is editorial information, not medical advice. Talk to your doctor before any treatment decision.

Sources: ClinicalTrials.gov PubChem

Updated 2026-09-19