Research / Unapproved

Somatostatin: Research Status, Structure, and Trial Data

Drafted by an automated content engine from FDA, PubChem, ClinicalTrials.gov, NIH DSLD, and Open Beauty Facts data.

Molecular formulaC76H104N18O19S2
Molecular weight1637.9 g/mol
Registered trials564
PubChem CID16129706

What Somatostatin Is

Somatostatin is a peptide compound identified by PubChem CID 16129706, with a molecular formula of C76H104N18O19S2. No approved drug label is associated with this compound in the data reviewed, so no FDA-approved indications, mechanism statement, or brand names can be reported here. This monograph reflects its status as a compound studied in clinical research rather than an approved medication.

Trial Footprint

Somatostatin appears in 564 registered clinical trials. Sampled studies span several areas of clinical investigation. One completed Phase 4 trial compared endoscopic variceal ligation combined with a vasoconstrictor against ligation combined with a proton pump inhibitor for controlling acute esophageal variceal bleeding. Other completed studies without a designated phase examined dietary approaches in irritable bowel syndrome with a diarrheal variant, and the effects of diet on plasma chromogranin measurement in patients with neuroendocrine tumors. These entries illustrate the range of settings in which somatostatin has been studied, without indicating that any use is approved or established as effective.

FAQ

Is somatostatin FDA approved?
No approved label for somatostatin was found in the data reviewed for this monograph. It is discussed here as a compound studied in clinical research rather than as an approved medication.
What is somatostatin's chemical identity?
Somatostatin is a peptide with the molecular formula C76H104N18O19S2. It is catalogued in PubChem under CID 16129706.
How many clinical trials have studied somatostatin?
Public trial registries list 564 registered trials involving somatostatin. Sampled studies include research in variceal bleeding management, irritable bowel syndrome, and neuroendocrine tumor diagnostics.
What kinds of studies have used somatostatin?
Sampled trials include a completed Phase 4 study comparing treatment approaches for acute esophageal variceal bleeding, and completed studies examining dietary factors in irritable bowel syndrome and in neuroendocrine tumor patients. These are examples from a much larger set of registered trials.
Are there reported side effects for somatostatin in this data?
No adverse event report data was available in the dataset used for this monograph, so no side effect summary can be provided here.
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Sources: PubChem ClinicalTrials.gov

Updated 2026-08-10