Approved

Palmitoyl Tripeptide-1: Uses, Evidence, and Safety

Molecular formulaC30H54N6O5
Molecular weight578.8 g/mol
Registered trials1
PubChem CID10231864
Brand namesBUDDATE REGES INTENSIVE TREATMENT

Anyone researching ingredients in topical skin creams may come across palmitoyl tripeptide-1 on a product label. Here is what the available labeling and trial data actually say about it.

Key takeaways

  • Palmitoyl tripeptide-1 is formulated as a topical cream product, marketed under the brand name BUDDATE REGES INTENSIVE TREATMENT.
  • The product label describes it as a cream applied to the skin, without listing a pharmacologic class or mechanism of action.
  • One registered trial references palmitoyl tripeptide-1, an AI-personalized skincare regimen study for facial photoaging, which has completed.
  • No boxed warning is associated with this product's labeling.
  • No adverse event reports were identified in the data reviewed.

What Palmitoyl Tripeptide-1 Is

Palmitoyl tripeptide-1 is a compound (PubChem CID 10231864) formulated into a topical cream intended for application to the skin. The available labeling does not specify a drug class or describe a mechanism of action.

What Palmitoyl Tripeptide-1 Is Approved For

Labeling for the brand BUDDATE REGES INTENSIVE TREATMENT describes it as a cream meant to be applied to areas of the body needing nourishment, massaged gently into the skin. The label does not describe a boxed warning for this product.

What the Evidence Shows

One trial in the registry involves palmitoyl tripeptide-1. That study, an AI-personalized skincare regimen for facial photoaging in women, has reached completed status. The trial registry does not list a development phase for this study.

Reported Side Effects

No adverse event reports for palmitoyl tripeptide-1 were found in the data reviewed. This does not necessarily mean no side effects occur, only that none appear in the dataset examined.

FAQ

What is palmitoyl tripeptide-1 used for?
Based on available labeling, palmitoyl tripeptide-1 is formulated into a topical cream intended to be applied to the skin and gently massaged in. The label markets it under the brand name BUDDATE REGES INTENSIVE TREATMENT. No pharmacologic class or mechanism of action is specified in the data reviewed.
Does palmitoyl tripeptide-1 have a boxed warning?
No, the labeling data reviewed does not indicate a boxed warning for this product.
Is there clinical trial evidence for palmitoyl tripeptide-1?
One registered trial references this compound, an AI-personalized skincare regimen study for facial photoaging in women, which has completed. The registry does not specify a development phase for this trial.
What side effects are reported for palmitoyl tripeptide-1?
No adverse event reports for palmitoyl tripeptide-1 were identified in the data reviewed. The absence of reports in this dataset does not confirm the absence of side effects in general use.
What is the chemical identity of palmitoyl tripeptide-1?
Palmitoyl tripeptide-1 is catalogued under PubChem CID 10231864, with a molecular formula of C30H54N6O5. It is formulated as an ingredient in topical skin cream products.
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Sources: DailyMed label ClinicalTrials.gov PubChem

Updated 2026-11-07