Many people looking into skin creams for stretch marks or scars come across palmitoyl tetrapeptide-7 on an ingredient list and want to know what it actually does. Here is what the available labeling and trial data show about this compound.
Key takeaways
- Palmitoyl tetrapeptide-7 is marketed under the brand name Stretch Marks cream.
- Its labeled use is topical, aimed at scars, stretch marks, and skin elasticity.
- The label carries no boxed warning.
- One registered clinical trial and one sample trial are noted in available data, though the sample trial evaluated a different treatment approach (Hydrafacial) rather than this peptide directly.
- No FAERS adverse event reports were found in the data reviewed.
What Palmitoyl Tetrapeptide-7 Is
Palmitoyl tetrapeptide-7 is classified in labeling under a non-standardized food allergenic extract category, which reflects a regulatory classification rather than a description of how it works on skin. The compound has a molecular weight of about 695 and is identified by PubChem CID 10078408. No detailed mechanism of action is provided in the label reviewed.
What Palmitoyl Tetrapeptide-7 Is Approved For
The labeled indication is for a stretch marks cream intended to reduce the appearance of scars and support skin elasticity. Labeling directs application over the body, with particular attention to the abdomen, applied each morning and evening. The product is marketed under the brand name Stretch Marks cream. The label does not carry a boxed warning.
What the Evidence Shows
Available data lists one registered clinical trial associated with this compound. A sample trial identified in the data, a completed Phase 4 study (NCT05932732), assessed facial skin quality, hydration, and skin barrier function following Hydrafacial treatments, but this trial evaluated a treatment modality rather than palmitoyl tetrapeptide-7 itself. No trials specific to this peptide's efficacy were identified in the data reviewed.
Reported Side Effects
No adverse event reports were identified for palmitoyl tetrapeptide-7 in the data reviewed. This does not necessarily mean no side effects occur, only that none were captured in the dataset consulted.