Approved

Palmitoyl Pentapeptide-4: Uses And Safety Overview

Drafted by an automated content engine from FDA, PubChem, ClinicalTrials.gov, NIH DSLD, and Open Beauty Facts data.

Molecular formulaC39H75N7O10
Molecular weight802.1 g/mol
Registered trials0
PubChem CID9897237
Drug classNon-Standardized Food Allergenic Extract [EPC]
Brand namesStretch Marks cream

Key takeaways

  • Palmitoyl pentapeptide-4 is a synthetic peptide formulated into a topical stretch mark cream.
  • The labeled use is cosmetic: supporting skin elasticity and softening the appearance of scars and stretch marks.
  • No mechanism of action is described on the label.
  • No clinical trials are registered for this compound, and no adverse event reports are on file.

What Palmitoyl Pentapeptide-4 Is

Palmitoyl pentapeptide-4 is a small peptide (PubChem CID 9897237) built from a fatty acid chain attached to a short amino acid sequence. It is manufactured as a cosmetic ingredient rather than a systemic drug. The label classifies the product under a non-standardized allergenic extract category, which reflects how the filing was coded rather than a pharmacological drug class.

What Palmitoyl Pentapeptide-4 Is Approved For

The label covers a single product, a Stretch Marks cream, intended to reduce the appearance of scars and improve skin elasticity. Directions on the label call for applying the cream over the body, with emphasis on the abdomen, each morning and evening. This is a topical cosmetic use rather than a treatment for an underlying medical condition.

What the Evidence Shows

No clinical trials are registered for palmitoyl pentapeptide-4. There is no trial-based evidence available to describe here, and none is claimed on the label.

FAQ

What is palmitoyl pentapeptide-4 used for?
It is formulated into a topical stretch mark cream intended to support skin elasticity and soften the look of scars and stretch marks. It is applied directly to the skin rather than taken internally.
Is palmitoyl pentapeptide-4 an FDA-approved drug?
It is marketed as a cosmetic ingredient under a labeled stretch mark cream product rather than as an FDA-approved therapeutic drug. The available label describes cosmetic directions for use, not disease treatment.
How does palmitoyl pentapeptide-4 work?
The available label does not describe a mechanism of action for this ingredient. It is a peptide combined with a fatty acid chain, used within a cosmetic formulation.
Are there clinical trials on palmitoyl pentapeptide-4?
No clinical trials are currently registered for this compound. This means there is no trial-based safety or efficacy data available to summarize.
What side effects are reported for palmitoyl pentapeptide-4?
No adverse event reports are on file for this ingredient in the data reviewed. This reflects an absence of reported cases rather than confirmation of safety.
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Sources: DailyMed label PubChem

Updated 2026-08-04