Key takeaways
- Palmitoyl pentapeptide-4 is the active ingredient in a labeled topical cream marketed for stretch marks and skin elasticity.
- Its labeled brand name is Stretch Marks cream, applied to the skin rather than taken systemically.
- No mechanism of action is described in the available label text.
- No clinical trials are registered for this compound in the data reviewed.
- No adverse event reports were found in the FAERS data reviewed for this compound.
What Palmitoyl Pentapeptide-4 Is
Palmitoyl pentapeptide-4 is a lab-made peptide attached to a fatty acid chain (palmitic acid), a structure common in cosmetic ingredients designed for skin application. The label classifies it under a non-standardized food allergenic extract category, though no mechanism of action is described in the data reviewed. It is formulated as a topical cream product rather than an injectable or oral compound.
What Palmitoyl Pentapeptide-4 Is Approved For
The labeled product, Stretch Marks cream, is described as intended to reduce the appearance of scars and stretch marks and to support skin elasticity. Labeling directs application over the body, with emphasis on the abdomen, applied to the skin each morning and evening. No boxed warning is present on this label.
What the Evidence Shows
The data reviewed shows no registered clinical trials for palmitoyl pentapeptide-4. This means the labeled claims are not supported here by trial data in the sources reviewed.