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Nesiritide: Research Status and Clinical Trial Data

Molecular formulaC143H244N50O42S4
Molecular weight3464 g/mol
Registered trials1861
PubChem CID71308561

What Nesiritide Is

Nesiritide is a peptide compound identified by PubChem CID 71308561, with a molecular formula of C143H244N50O42S4. No FDA-approved product label is present in this dataset, so this overview covers identity and trial activity only, without claims about approved uses or effectiveness.

Trial Footprint

Registries list 1,861 total trials associated with nesiritide. Sample entries include a Phase 2 study of CM-101 in systemic sclerosis patients that is currently suspended, a not-yet-recruiting study on postpartum CO rehabilitation, and a completed Phase 2 study (DOVA) examining the aquaretic tolvaptan and its effect on the nitric oxide system. These examples illustrate the range of research contexts in which the compound or related agents have been studied, from cardiovascular physiology to postpartum recovery.

FAQ

Is nesiritide FDA-approved?
Based on the available data, there is no FDA-approved label on file for nesiritide. It should be considered a research-stage compound rather than an approved therapy.
How many clinical trials have studied nesiritide?
Registries show 1,861 total trials associated with nesiritide. These span multiple phases and study designs, though not all are specific to nesiritide itself.
What kinds of studies have involved nesiritide?
Sample trials include research into systemic sclerosis treatment, postpartum cardiac output rehabilitation, and the nitric oxide system in the context of aquaretic therapy. These examples show a range of research areas rather than a single confirmed use.
Are there known side effects of nesiritide?
No adverse event report data was available in this dataset, so no side effect summary can be provided at this time.
What is the molecular structure of nesiritide?
Nesiritide has the molecular formula C143H244N50O42S4 and a molecular weight of approximately 3464. It is cataloged under PubChem CID 71308561.
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Sources: PubChem ClinicalTrials.gov

Updated 2026-09-19