Research / Unapproved

LL-37 Peptide: Research Status and Trial Overview

Drafted by an automated content engine from FDA, PubChem, ClinicalTrials.gov, NIH DSLD, and Open Beauty Facts data.

Molecular formulaC205H340N60O53
Molecular weight4493 g/mol
Registered trials61
PubChem CID16198951

Key takeaways

  • LL-37 has no FDA-approved label and is not authorized for any medical use.
  • It is a large peptide compound with a molecular weight near 4,493 daltons.
  • At least 61 studies referencing LL-37 are registered on clinicaltrials.gov.
  • Sample trial records in this dataset focus on related supplementation topics rather than LL-37 administration itself.

What LL-37 is

LL-37 is the name given to a peptide compound identified by PubChem CID 16198951, with the molecular formula C205H340N60O53. It is composed of a long chain of amino acids linked into a single peptide molecule. No FDA-approved drug label exists for LL-37, meaning there is no approved indication, mechanism statement, or authorized brand name to reference at this time. It remains a subject of research rather than an approved therapeutic.

Trial footprint

Registries list 61 trials associated with LL-37 research. Records included in this dataset show a mix of statuses and designs, though several examples center on related supplementation research rather than direct LL-37 administration. One withdrawn study examined vitamin D in active tuberculosis. Another, completed study looked at fermented milk and its effect on winter infectious disease occurrence, and a separate completed trial assessed vitamin D supplementation and aerobic fitness in athletes. These examples illustrate the breadth of the surrounding research landscape captured under LL-37 related searches, rather than a single defined program.

FAQ

Is LL-37 an FDA-approved drug?
No. LL-37 does not have an FDA-approved label, indication, or authorized brand name. It is currently classified as an unapproved research compound.
What is LL-37 chemically?
LL-37 is a peptide with the molecular formula C205H340N60O53 and a molecular weight of about 4,493 daltons. It is identified in chemical databases under PubChem CID 16198951.
How many clinical trials involve LL-37?
Public registries list 61 trials associated with LL-37 research. The specific designs, phases, and outcomes of these studies vary widely.
Do the sample trials show LL-37 was tested directly?
The available trial examples in this dataset, covering vitamin D and fermented milk supplementation, relate to broader research areas rather than direct LL-37 dosing studies. This reflects the range of related research rather than a confirmed LL-37 clinical program.
Are there known side effects of LL-37 from adverse event reports?
No adverse event report data is available for LL-37 in this dataset, so no side effect pattern can be summarized at this time.
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Sources: PubChem ClinicalTrials.gov

Updated 2026-08-03