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Ibutamoren: Clinical Trial Evidence and Overview

Drafted by an automated content engine from FDA, PubChem, ClinicalTrials.gov, NIH DSLD, and Open Beauty Facts data.

Molecular formulaC27H36N4O5S
Molecular weight528.7 g/mol
Registered trials8
PubChem CID178024

Ibutamoren is a compound studied for its potential effects on growth hormone activity, and many people encounter it while researching options for muscle wasting, growth disorders, or metabolic conditions. Current research spans several patient populations and disease areas, though findings vary by trial and stage of development.

Key takeaways

  • Eight clinical trials have registered ibutamoren as a study compound across different conditions.
  • A phase 3 trial (LUM-201) is currently recruiting children with growth hormone deficiency.
  • A completed phase 2 study examined ibutamoren's effects on nonalcoholic fatty liver disease.
  • A phase 2 trial evaluating ibutamoren for sarcopenia in post-hip fracture patients was terminated before completion.
  • The compound has a molecular weight of about 528.7 g/mol (PubChem CID 178024).

What the evidence shows

Clinicaltrials.gov lists eight registered trials involving ibutamoren, reflecting interest across pediatric, metabolic, and musculoskeletal research areas. One notable phase 3 trial is recruiting children with growth hormone deficiency to assess a related formulation. A separate phase 2 trial, now completed, investigated whether ibutamoren affects nonalcoholic fatty liver disease. A phase 2 study looking at sarcopenia following hip fracture was terminated before reaching its conclusions, illustrating that not all research in this area has been completed as planned.

FAQ

What is ibutamoren being studied for?
Ibutamoren has been investigated in clinical trials covering growth hormone deficiency, nonalcoholic fatty liver disease, and sarcopenia following hip fracture. These studies span different phases and patient populations. Not all trials have reached completion, and results vary by study.
How many clinical trials have looked at ibutamoren?
Clinicaltrials.gov lists eight registered trials involving ibutamoren. These trials cover a range of phases, from early testing to a phase 3 study in children with growth hormone deficiency.
Is there a phase 3 trial for ibutamoren?
Yes, a phase 3 trial known as LUM-201 is currently recruiting children with growth hormone deficiency. This is the most advanced registered trial involving ibutamoren to date.
Did any ibutamoren trials get stopped early?
Yes, a phase 2 trial studying ibutamoren for sarcopenia in post-hip fracture patients was terminated before completion. Publicly available data does not specify the reason for termination.
What is the chemical identity of ibutamoren?
Ibutamoren has the molecular formula C27H36N4O5S and a molecular weight of approximately 528.7 g/mol. It is catalogued under PubChem CID 178024.
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Sources: PubChem ClinicalTrials.gov trial records

Updated 2026-08-03