Approved

GHK-Cu: Uses, Research, and Side Effects

Molecular formulaC14H21CuN6O4-
Molecular weight400.9 g/mol
Registered trials3
PubChem CID139035031

Many people encounter GHK-Cu through skincare products or research discussions and want to know what it actually is. Here is what the available data shows, without the marketing language.

Key takeaways

  • GHK-Cu is a copper-binding peptide with the molecular formula C14H21CuN6O4 and a molecular weight near 400.9.
  • No FDA label details (indications, mechanism, or approved brand names) were provided in this dataset.
  • Three registered clinical trials reference GHK-Cu, spanning completed, recruiting, and not-yet-recruiting stages.
  • Current trial interest centers on facial skin quality, topical wound healing, and circulating GHK-Cu levels after patch use.
  • No FAERS adverse event reports were available for this compound.

What GHK-Cu is

GHK-Cu is a small peptide that binds copper, identified in PubChem under CID 139035031. Beyond its chemical identity, no FDA label information on drug class or mechanism was available in this dataset, so no claims about how it works in the body are made here.

What the evidence shows

Three clinical trials reference GHK-Cu in the available records. One completed Phase 4 trial assessed facial skin quality, hydration, and skin barrier effects across three treatment sessions in adults of all skin types. A separate Phase 2 trial, currently recruiting, is evaluating a topical GHK-Cu gel for acute skin wound healing. A third study, not yet recruiting, plans to examine how a patch affects circulating GHK and GHK-Cu levels in healthy adults.

Reported side effects

No adverse event reports were available for GHK-Cu in this dataset, so no side effect pattern can be summarized at this time.

FAQ

What is GHK-Cu?
GHK-Cu is a copper-binding peptide with the chemical formula C14H21CuN6O4 and a molecular weight of about 400.9. It is identified in PubChem under CID 139035031. No FDA label mechanism or drug class information was available in this dataset.
Is GHK-Cu FDA approved?
This dataset did not include FDA label indications, mechanism, or brand name information for GHK-Cu. Without that data, no approved use can be confirmed or described here.
What clinical trials have studied GHK-Cu?
Three registered trials reference GHK-Cu. One completed Phase 4 trial looked at facial skin quality and hydration, a recruiting Phase 2 trial is studying a topical gel for wound healing, and a third trial not yet recruiting will examine circulating GHK-Cu levels after patch application.
Are there known side effects of GHK-Cu?
No adverse event reports were available in this dataset for GHK-Cu. This means no side effect pattern can currently be summarized from reported data.
Is GHK-Cu the same as the compounds used in skincare products?
The dataset identifies GHK-Cu by its chemical structure and confirms research trials involving topical formulations. It does not provide details linking this specific identifier to any particular commercial product.
This page is an editorial information resource. It does not sell, prescribe, or recommend any medication. Content is editorial information, not medical advice. Talk to your doctor before any treatment decision.

Sources: PubChem CID 139035031 ClinicalTrials.gov (NCT05932732, NCT07437586, NCT07706361)

Updated 2026-09-19