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Felypressin: Identity and Research Trial Status

Drafted by an automated content engine from FDA, PubChem, ClinicalTrials.gov, NIH DSLD, and Open Beauty Facts data.

Molecular formulaC46H65N13O11S2
Molecular weight1040.2 g/mol
Registered trials2
PubChem CID14257662

Felypressin sometimes comes up in discussions of dental anesthesia, but it carries no FDA-approved label and is not sold as an approved drug in the United States. What exists publicly is a small clinical trial footprint and basic chemical identity data.

What felypressin is

Felypressin is a synthetic peptide with the molecular formula C46H65N13O11S2 and a molecular weight of about 1,040.2 (PubChem CID 14257662). No approved product label, indication, or mechanism-of-action statement is available for this compound in the data reviewed.

Regulatory status

Felypressin is unapproved and classified as a research compound. There is no dosing information, brand name, or labeled use to report.

Trial footprint

Two clinical trials are registered in connection with felypressin. One is a completed Phase 1 study evaluating liposomal prilocaine for maxillary infiltration anesthesia. The other is a completed Phase 4 study comparing articaine and prilocaine for maxillary tooth extraction. Neither trial record available here reports outcome data specific to felypressin itself.

FAQ

Is felypressin FDA approved?
No. Felypressin has no approved drug label in the United States and is considered an unapproved research compound. No brand name or approved indication exists for it in the data reviewed.
What is felypressin chemically?
Felypressin is a synthetic peptide with the molecular formula C46H65N13O11S2 and a molecular weight of roughly 1,040.2. It is catalogued in PubChem under CID 14257662.
How many clinical trials involve felypressin?
Two clinical trials are registered in connection with felypressin. Both are completed studies related to dental local anesthesia, one in Phase 1 and one in Phase 4.
What did the felypressin-related trials study?
One completed Phase 1 trial evaluated liposomal prilocaine for maxillary infiltration anesthesia. A separate completed Phase 4 trial compared articaine and prilocaine for extracting maxillary teeth.
Are there known side effects of felypressin?
No adverse event report data was available for felypressin in the sources reviewed, so no side effect pattern can be summarized at this time.
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Sources: PubChem ClinicalTrials.gov

Updated 2026-08-04