Enfuvirtide: Research Status and Trial Data Overview

What enfuvirtide is

Enfuvirtide is a large synthetic peptide with the molecular formula C204H301N51O64 and a molecular weight of approximately 4,492 daltons (PubChem CID 16130199). No FDA-approved product label is included in the data reviewed for this monograph, and this article does not describe an approved medical use.

Regulatory status

Enfuvirtide's regulatory status is classified as unapproved research in the data reviewed here. No indications, mechanism summary, or approved brand information were available from a label source to include in this monograph.

Trial footprint

There are 61 registered clinical trials associated with enfuvirtide. Among the sample of studies reviewed, one titled "An Observational Study of Induction Therapy With Fuzeon (Enfuvirtide) in Combination With Antiretroviral Drugs in Patients With HIV-1 Infection" (NCT01902615) is listed as completed. A second, "Cohort Study for Patients Using Fuzeon (Enfuvirtide)" (NCT00216359), has an unknown status. A third trial, focused on the effects of anti-HIV therapy on the immune systems of children and young adults infected with HIV (NCT00004735), is also listed as completed. These entries reflect study registration records only and do not indicate outcomes or efficacy.