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Ecnoglutide: Research Status and Trial Data

Molecular formulaC194H304N48O61
Molecular weight4285 g/mol
Registered trials15
PubChem CID162625103

What Ecnoglutide Is

Ecnoglutide, also studied under the codes XW003 and VRB-101, is a large synthetic peptide compound with a molecular formula of C194H304N48O61. It has no FDA-approved label, and no brand name has been assigned. It is classified here as an investigational research compound, meaning any use outside of registered clinical trials falls outside its current regulatory status.

Trial Footprint

Ecnoglutide has 15 registered clinical trials. Among the available examples, a Phase 1 study examined its use in Chinese adolescents with obesity and has completed. A Phase 3 study compared it with placebo in patients with type 2 diabetes and has also completed. A separate Phase 2 study looked at a weekly oral formulation of ecnoglutide in participants with obesity or overweight and related comorbidities, and it has completed as well. These listings describe trial activity only and do not establish safety or effectiveness for any use.

FAQ

Is ecnoglutide FDA approved?
No. Ecnoglutide does not have an FDA-approved label or brand name. It remains an investigational compound studied in clinical research settings.
What is ecnoglutide also known as?
Ecnoglutide has been studied under the research codes XW003 and VRB-101. These names appear across its registered clinical trial records.
How many clinical trials have studied ecnoglutide?
There are 15 registered clinical trials involving ecnoglutide. These span different phases and study populations, including trials in obesity and type 2 diabetes.
What has ecnoglutide been studied for in trials?
Registered trials have examined ecnoglutide in people with obesity, overweight with weight-related comorbidities, and type 2 diabetes. A Phase 3 trial compared it with placebo in a type 2 diabetes population, and other studies have tested an oral formulation.
What kind of compound is ecnoglutide?
Ecnoglutide is a large synthetic peptide with the molecular formula C194H304N48O61. It is cataloged in PubChem for chemical reference purposes.
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Sources: ClinicalTrials.gov PubChem

Updated 2026-11-07