Approved

Corticorelin: Uses, Evidence, and Trial Data

Drafted by an automated content engine from FDA, PubChem, ClinicalTrials.gov, NIH DSLD, and Open Beauty Facts data.

Molecular formula	C208H344N60O63S2
Molecular weight	4757 g/mol
Registered trials	96
PubChem CID	16186200

Anyone researching corticorelin usually wants to know what it does in the body and how much clinical study actually backs it. This overview summarizes what is publicly registered about the compound's research footprint, without going into label specifics that were not provided in this dataset.

Key takeaways

Corticorelin is a large synthetic peptide with the molecular formula C208H344N60O63S2.
It has a molecular weight of approximately 4,757 g/mol, consistent with a multi-residue peptide.
A DailyMed label listing exists for corticorelin, indicating it has been formally documented.
At least 96 trials referencing corticorelin are registered, spanning multiple areas of investigation.
Sample trial records include Cushing syndrome diagnostic work and pediatric endocrine research.

What corticorelin is

Corticorelin is a synthetic peptide compound identified by PubChem CID 16186200. Its structure is a long chain of amino acids linked in sequence, characteristic of a corticotropin-releasing hormone analog. Specific label details on drug class and mechanism were not available in this dataset, so no further claims about its pharmacological classification are made here.

What the evidence shows

Public registries list 96 total trials referencing corticorelin. One completed study, "Jugular Vein Sampling for Hormone Levels for the Diagnosis of Cushing Syndrome," used corticorelin-related testing in the diagnostic workup for Cushing syndrome. A separate Phase 1 study, examining safety, pharmacokinetics, and pharmacodynamics of a related compound in adolescent females with congenital adrenal hyperplasia, was withdrawn before completion. A third listed trial, focused on skin-to-skin care for preterm infants, is currently recruiting and is not phase-classified. Together these records show a research footprint concentrated in endocrine diagnostics and hormone physiology rather than a single large late-stage program.

Reported side effects

No FAERS adverse event report data was available for corticorelin in this dataset, so no side effect summary can be provided here.

FAQ

What is corticorelin?

Corticorelin is a synthetic peptide compound with a large, multi-amino-acid structure and a molecular weight of about 4,757 g/mol. It is documented in a formal drug label listing. Detailed mechanism and classification information was not available in this dataset.

How many clinical trials have studied corticorelin?

Public trial registries list at least 96 trials referencing corticorelin. These span different research areas, including endocrine diagnostics and hormone-related pediatric studies.

Has corticorelin been used in Cushing syndrome research?

Yes, one completed trial used corticorelin-related testing as part of jugular vein sampling to help diagnose Cushing syndrome. This reflects its historical role in endocrine diagnostic research rather than an established treatment use.

Are there known side effects of corticorelin?

This dataset did not include adverse event report data for corticorelin, so a side effect summary cannot be provided here. Reported side effects, when available from safety databases, reflect report counts rather than confirmed causation.

Is corticorelin approved for a specific medical use?

A formal label listing exists for corticorelin, but specific approved indications were not detailed in the available dataset. Readers should consult the official label or a healthcare professional for indication-specific information.

This page is an editorial information resource. It does not sell, prescribe, or recommend any medication. Content is editorial information, not medical advice. Talk to your doctor before any treatment decision.

Sources: PubChem CID 16186200 DailyMed label listing ClinicalTrials.gov trial registry

Updated 2026-08-10