Home › Encyclopedia › Cibinetide (ARA 290): Research Status and Trial Data
Research / Unapproved

Cibinetide (ARA 290): Research Status and Trial Data

Registered trials4
PubChem CID91810664

What Cibinetide Is

Cibinetide, also studied under the name ARA 290, is a peptide compound (PubChem CID 91810664) that has not received FDA approval and carries no approved drug label. It remains classified as an investigational research compound, meaning any use outside registered clinical trials falls outside its studied context.

Trial Footprint

Cibinetide has been the subject of 4 registered clinical trials. Sampled studies have examined corneal nerve fiber density and neuropathic symptoms in sarcoidosis, cognitive and neural effects, and diabetic macular oedema. The sarcoidosis trial (NCT02039687) and the cognitive effects trial (NCT02070783) both reached Phase 2 (or Phase 1/2) and are listed as completed. A separate diabetic macular oedema trial (NCT06626971) was terminated at the Phase 2 stage. This spread of trial statuses reflects an active but limited and incomplete research record, not a demonstrated therapeutic benefit.

FAQ

Is cibinetide FDA-approved?
No. Cibinetide, also known as ARA 290, has no FDA-approved label and is classified as an investigational research compound. It has not been evaluated or cleared for any medical use.
What conditions has cibinetide been studied for?
Registered trials have examined cibinetide in the context of sarcoidosis-related corneal nerve changes and neuropathic symptoms, cognitive and neural effects, and diabetic macular oedema. These studies do not establish that cibinetide is effective for any condition.
How many clinical trials have studied cibinetide?
Public trial registries list 4 clinical trials involving cibinetide. Their statuses range from completed to terminated, indicating the research base is still limited.
Was any cibinetide trial stopped early?
Yes. A Phase 2 trial evaluating cibinetide for diabetic macular oedema (NCT06626971) is listed as terminated. The available data do not specify a reason within this summary.
Can cibinetide be used outside of clinical trials?
Because cibinetide has no approved label and remains investigational, it has not been evaluated for safety or effectiveness outside of registered research settings.
This page is an editorial information resource. It does not sell, prescribe, or recommend any medication. Content is editorial information, not medical advice. Talk to your doctor before any treatment decision.

Sources: ClinicalTrials.gov PubChem

Updated 2026-09-19