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Research / Unapproved

Cibinetide (ARA290): Research Status and Trial Overview

Drafted by an automated content engine from FDA, PubChem, ClinicalTrials.gov, NIH DSLD, and Open Beauty Facts data.

Molecular formulaC51H84N16O21
Molecular weight1257.3 g/mol
Registered trials4
PubChem CID91810664

Cibinetide is an investigational peptide, also known in research literature as ARA290, that has not received approval from any regulatory agency for medical use. No prescribing label exists for this compound, and it is not sold as an approved drug under any brand name.

What cibinetide is

Cibinetide is a synthetic peptide with the molecular formula C51H84N16O21 and a molecular weight of approximately 1,257.3 g/mol (PubChem CID 91810664). It remains a subject of laboratory and clinical research rather than an approved therapeutic.

Trial footprint

Four trials involving cibinetide are registered on ClinicalTrials.gov. A completed Phase 1/2 study examined cognitive and neural effects of ARA290. A separate completed study evaluated corneal nerve fiber density and neuropathic symptoms in people with sarcoidosis. A third trial, focused on diabetic macular oedema, was registered but later terminated. These records reflect the scope of registered research rather than any demonstrated clinical benefit.

FAQ

Is cibinetide an approved medication?
No. Cibinetide has no approved regulatory label and is classified as an investigational compound. It is studied in research settings under names including ARA290.
What is cibinetide used for in research?
Registered trials have explored cibinetide in contexts such as cognitive and neural function, corneal nerve fiber density in sarcoidosis, and diabetic macular oedema. None of these studies establish an approved use, and one related trial was terminated before completion.
How many clinical trials have studied cibinetide?
Public registries list four clinical trials involving cibinetide. These span Phase 1 and Phase 2 designs, with statuses ranging from completed to terminated.
Is ARA290 the same as cibinetide?
Yes. ARA290 is the research name used in several clinical trial records for the compound known as cibinetide.
What is the chemical identity of cibinetide?
Cibinetide is a peptide with the molecular formula C51H84N16O21 and a molecular weight of about 1,257.3 g/mol, catalogued under PubChem CID 91810664.
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Sources: PubChem ClinicalTrials.gov

Updated 2026-08-03