Research / Unapproved

Cagrilintide: Research Status, Trials, and What It Is

Molecular formulaC194H312N54O59S2
Molecular weight4409 g/mol
Registered trials45
PubChem CID171397054

Regulatory status

Cagrilintide is an investigational compound. It does not have an approved drug label, and no regulatory agency has cleared it for medical use. Any research findings described below relate to ongoing clinical study, not an established use.

What cagrilintide is

Cagrilintide is a long chain peptide with the molecular formula C194H312N54O59S2 and a molecular weight of approximately 4,409 g/mol (PubChem CID 171397054). Because it lacks an approved label, there is no FDA-defined mechanism, indication, or dosing information to report.

Trial footprint

Cagrilintide has 45 registered clinical trials. Sampled studies include a trial comparing two injectable versions of cagrilintide against placebo in people with excess body weight, a study examining how a cagrilintide and semaglutide combination affects food intake, appetite, and stomach emptying, and a study comparing blood levels of cagrilintide and semaglutide given together versus separately. These trials involve people with overweight or obesity and remain part of an active research program.

FAQ

Is cagrilintide FDA approved?
No. Cagrilintide is an investigational compound and does not currently have an FDA-approved label or indication. It remains under study in clinical trials.
What is cagrilintide made of?
Cagrilintide is a peptide with the molecular formula C194H312N54O59S2 and a molecular weight of about 4,409 g/mol. It is cataloged in PubChem under CID 171397054.
How many clinical trials involve cagrilintide?
There are 45 registered clinical trials involving cagrilintide. Sampled trials include studies in people with excess body weight or obesity, some evaluating it alongside semaglutide.
What is CagriSema?
CagriSema is a name used in trials that study cagrilintide combined with semaglutide. Registered studies have looked at its effects on food intake, appetite, and stomach emptying, as well as combined versus separate injection blood levels.
Does cagrilintide have known side effects?
No adverse event report data was available for cagrilintide at this time. Because it is investigational, safety information is limited to what is disclosed within individual clinical trial results.
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Sources: PubChem ClinicalTrials.gov

Updated 2026-09-19