Home › Encyclopedia › Acetyl Hexapeptide-8: Label, Uses, and Trial Data
Approved

Acetyl Hexapeptide-8: Label, Uses, and Trial Data

Drafted by an automated content engine from FDA, PubChem, ClinicalTrials.gov, NIH DSLD, and Open Beauty Facts data.

Molecular formulaC35H62N14O11S
Molecular weight887 g/mol
Registered trials6
PubChem CID71587772
Drug classNon-Standardized Food Allergenic Extract [EPC]
Brand namesStretch Marks cream

Key takeaways

  • Acetyl hexapeptide-8 is the active ingredient in a labeled topical product called Stretch Marks cream.
  • The label describes it as intended to reduce the appearance of stretch marks and support skin elasticity.
  • No boxed warning appears on the label.
  • Six trials involving acetyl hexapeptide-8 are registered, spanning cosmetic and ophthalmic research contexts.
  • No FAERS reports are currently listed for this compound in the data reviewed.

What acetyl hexapeptide-8 is

Acetyl hexapeptide-8 is a synthetic peptide with a molecular weight near 887 (PubChem CID 71587772). Its label lists the pharmacologic class as a non-standardized food allergenic extract. No mechanism of action is described in the label data available.

What acetyl hexapeptide-8 is approved for

The FDA label covers a topical product marketed under the brand name Stretch Marks cream. It is described as intended to reduce the appearance of scars and stretch marks and to support skin repair and elasticity. The label does not carry a boxed warning.

What the evidence shows

Six trials involving acetyl hexapeptide-8 are registered. One completed study examined its topical use in relation to the cosmetic appearance of oily skin. Separate completed studies looked at the compound, referred to as AH8 or Argireline, in blepharospasm (phase 1/2) and in periorbital wrinkles (phase 3).

FAQ

What is acetyl hexapeptide-8 used for?
Per its FDA label, acetyl hexapeptide-8 is the active ingredient in a topical product called Stretch Marks cream. It is marketed to reduce the appearance of stretch marks and scars and to support skin elasticity.
Does acetyl hexapeptide-8 have a boxed warning?
No. The label on file for this compound does not carry a boxed warning.
How much clinical research exists on acetyl hexapeptide-8?
There are six registered trials involving this compound. They include studies on cosmetic skin appearance, blepharospasm, and periorbital wrinkles, all reported as completed.
Are there known side effects reported for acetyl hexapeptide-8?
No adverse event reports are currently listed in the data reviewed for this compound. This does not confirm an absence of side effects, only that none appear in the available reporting data.
What brand name is associated with acetyl hexapeptide-8?
The FDA label identifies it under the brand name Stretch Marks cream, a topical cosmetic product.
This page is an editorial information resource. It does not sell, prescribe, or recommend any medication. Content is editorial information, not medical advice. Talk to your doctor before any treatment decision.

Sources: DailyMed label ClinicalTrials.gov PubChem FAERS

Updated 2026-08-04